Some extreme obesity is genetic, is it ...?

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iRuleThisForum Joined: 23 Jul 2004 Posted: Mon Oct 04, 2004 10:49 am	Post subject: Some extreme obesity is genetic, is it ...? New research suggests that changes to a gene involved in the regulation of body weight may contribute to weight gain in a very small number of obese individuals; I have hard time believing this. We mentioned about a couple of incidents related to some extreme obesity; someone weighed over 1000 pounds. We don't hear incidents like those reported in Europe or Asia. Is extreme obesity really genetic?


cloningOk Joined: 25 Jul 2004 Posted: Sat Oct 09, 2004 9:26 am	Post subject: Quote: We don't hear incidents like those reported in Europe or Asia. Is extreme obesity really genetic? Agreed. There is nothing original about Americans in terms of human genetics as they are from some part of the world originally. It seems rather strange that they are genetically different; therefore, one third of Americans have serious weight problem.

Thais Joined: 07 Aug 2004 Location: UK Posted: Sat Oct 09, 2004 9:59 am	Post subject: I would hazard a guess that the only genetic obesity is due to thyroid imbalance.

iRuleThisForum Joined: 23 Jul 2004 Posted: Sun Oct 10, 2004 7:30 am	Post subject: Thais wrote: I would hazard a guess that the only genetic obesity is due to thyroid imbalance. Function of the thyroid In areas where iodine - essential for the production of thyroxin - is lacking in the diet, the thyroid gland can be considerably enlarged, resulting in the swollen necks of endemic goitre. Thyroxin is critical to the regulation of metabolism and growth, throughout the animal kingdom. Among amphibians, for example, administering a thyroid-blocking agent such as propylthiouracil can prevent tadpoles from metamorphosing into frogs; conversely, administering thyroxin will trigger metamorphosis. In humans, children born with thyroid hormone deficiency will not grow well, and brain development can be severely impaired, in the condition referred to as cretinism. Newborn children in many developed countries are now routinely tested for thyroid hormone deficiency; this is done by analysis of a small drop of blood from the child (usually, the blood also is tested for phenylketonuria and several other metabolic diseases of genetic etiology). Children with thyroid hormone deficiency are easily treated by supplementation with synthetic thyroxin, which enables them to grow and develop normally. Because of the thyroid's selective uptake and extreme concentration of what is actually a quite rare element, it is extremely sensitive to the effects of various radioactive isotopes of iodine produced by nuclear fission. In the event of large accidental releases of such material into the environment, the uptake of radioactive iodine by the thyroid can, in theory, be blocked by saturating the uptake mechanism with a large surplus of non-radioactive iodine, taken in the form of iodide tablets. While biological researchers making compounds labeled with iodine isotopes do this, in the wider world such preventive measures are usually not stockpiled before an accident, nor are they distributed adequately afterward - one consequence of the Chernobyl disaster was an increase in thyroid cancers in the years following the accident. The document was originally published at Wikipedia and the document is licensed under GNU Free Document License. If you'd like to find out more about obesity, you might be interested in visiting this page in Wikipedia. So you are saying that, if you gain weight because of some medical condition, it has to do with metabolism.

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